Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways
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منابع مشابه
Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways
Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as atm/tefu, mre11, or rad50 disrupt telomere protection and localization of the telomere-associated proteins HP1 and HOAP, suggesting that recognition of chromosome ends contributes to telomere protection....
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2006
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.0020071